DuPont Nutrition & Biosciences recently released the findings of a first-time new study showing the effects Care4U 2’-FL had on dental caries-associated bacterium Streptococcus mutans. Previously, HMOs have not been studied for their effects on oral bacteria, but as HMOs are increasingly being added to infant formula, it is important to evaluate effects on oral microflora and potential impact on oral health.
“Human milk is known to contain factors that protect against caries,so we were interested to know how HMOs, and especially 2’-FL, affect S.mutans, one of the most studied bacteria related to dental caries, said Johanna Hirvonen, senior scientist, DuPont Nutrition & Biosciences. “This study was a collaboration between University of Turku, Institute of Dentistry and DuPont Nutrition & Biosciences. We evaluated the ability of S. mutansto grow on 2’-fucosyllactose (2’-FL) in comparison to galacto-oligosaccharides (GOS), lactose, and xylitol. The effects of 2’-FL, GOS, lactose, and xylitol on adhesion properties of S. mutans were also evaluated. While this study was done under in vitro conditions, it showed the differences between the studied carbohydrates, especially in S.mutans growth.”
“Though it is known that S.mutans can metabolise many carbon sources, we found that S.mutans was unable to grow on 2’-FL, while it grew well on GOS and lactose. Xylitol, as known before, reduced the growth of S. mutans,” added Krista Salli,scientist, DuPont Nutrition & Biosciences. “Thus, the data suggests that addition of 2’-FL to infant formula would not support the growth of S. mutans. The results highlight the selectivity of2’-FL consumption by oral bacteria.”
Adhesion to tooth surfaces is the first requirement for a biofilm—dental plaque–formation, 2’-FL decreased the adhesive properties of some of the studiedS. mutans strains. In infancy, oral microbiota develops, and delays colonisation of potentially pathogenic bacteria is vital. DuPont is expanding on this line of researchwith other oral bacteria and additional HMOs
News & Updates
Ferrero North America, one of the fastest growing confections …
Read More
Read More
“We do not anticipate any reduction in milk prices …
Read More
Read More
Ingredion will showcase its latest ingredient innovations at this …
Read More
Read More
Bonn Group of Industries, one of India’s leading manufacturers …
Read More
Read More
India’s fastest – growing coffee chain, Nothing Before Coffee …
Read More
Read More
Gemini, Cargill’s flagship edible oil brand and market leader …
Read More
Read More
The Food Authority, FSSAI, has re-operationalised the standards for …
Read More
Read More
This May, Magnolia Bakery fills the shelves with two …
Read More
Read More
Amiel Gourmet, a collective establishment of modern French cuisine …
Read More
Read More
Café Treat at Pride Plaza Hotel Ahmedabad is celebrating …
Read More
Read More