DuPont Nutrition & Biosciences recently released the findings of a first-time new study showing the effects Care4U 2’-FL had on dental caries-associated bacterium Streptococcus mutans. Previously, HMOs have not been studied for their effects on oral bacteria, but as HMOs are increasingly being added to infant formula, it is important to evaluate effects on oral microflora and potential impact on oral health.
“Human milk is known to contain factors that protect against caries,so we were interested to know how HMOs, and especially 2’-FL, affect S.mutans, one of the most studied bacteria related to dental caries, said Johanna Hirvonen, senior scientist, DuPont Nutrition & Biosciences. “This study was a collaboration between University of Turku, Institute of Dentistry and DuPont Nutrition & Biosciences. We evaluated the ability of S. mutansto grow on 2’-fucosyllactose (2’-FL) in comparison to galacto-oligosaccharides (GOS), lactose, and xylitol. The effects of 2’-FL, GOS, lactose, and xylitol on adhesion properties of S. mutans were also evaluated. While this study was done under in vitro conditions, it showed the differences between the studied carbohydrates, especially in S.mutans growth.”
“Though it is known that S.mutans can metabolise many carbon sources, we found that S.mutans was unable to grow on 2’-FL, while it grew well on GOS and lactose. Xylitol, as known before, reduced the growth of S. mutans,” added Krista Salli,scientist, DuPont Nutrition & Biosciences. “Thus, the data suggests that addition of 2’-FL to infant formula would not support the growth of S. mutans. The results highlight the selectivity of2’-FL consumption by oral bacteria.”
Adhesion to tooth surfaces is the first requirement for a biofilm—dental plaque–formation, 2’-FL decreased the adhesive properties of some of the studiedS. mutans strains. In infancy, oral microbiota develops, and delays colonisation of potentially pathogenic bacteria is vital. DuPont is expanding on this line of researchwith other oral bacteria and additional HMOs
News & Updates
An Ishida packing line solution comprising a multihead weigher, …
Read More
Read More
Kurkure, one of India’s most loved snack brands, started …
Read More
Read More
The FSSAI has decided to operationalise the draft regulations …
Read More
Read More
Ferrero is adding several new products to its Valentine’s …
Read More
Read More
The Confederation of Indian Industries (CII) hosted the 13th …
Read More
Read More
The FSSAI has decided to allow instant modification in …
Read More
Read More
Today, brand Pepsi is excited to announce a new …
Read More
Read More
Looking at the importance and increased need for front …
Read More
Read More
Nestlé India has launched ThickenUp Clear, a food and …
Read More
Read More
Marico Limited, one of India’s leading FMCG companies today …
Read More
Read More